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Freeze Drying

Lyophilization, commonly referred to as freeze drying, is the process of removing water from a product by sublimation and desorption. The freeze drying process is optimised by the introduction of solvents and gas species to improve product quality and to enhance the drying process.

 

Hiden's gas analysers provide detailed information about the gas/vapour composition during both the primary and secondary drying phases. Detection of the on-set of the secondary drying phase is readily detected. Analysis during the secondary drying phase enables a reduction in process cycle time and provides end point detection. Accurate determination of a user defined process 'end point' enables high consistency in product yield from batch to batch.

 

 

Products

 

 

RGA for vacuum, process monitoring and leak detection.

 

 

Brochures

 

icon QIC Series Gas Analysers (636K)

 

 

Presentations

 

icon Monitor and Control Freeze Drying with the HPR30 Vacuum Process Monitor (395K)

 

 

 

 

Application Notes

 

icon Moisture Sorption into Polymer Films using the Response Test Method (73K)

icon QIC20 Fragrance Fingerprinting (151K)