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Our thanks to Prof David Lloyd
(Biology Dept., University of Wales, Cardiff)
for this list of published papers from his research group activity.
Many of these publications illustrate
the practical use and capability
of the HPR-40 system as a dissolved species probe.
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| 1 |
Oxidative detoxification of hydrogen
sulphide detected by mass spectrometry in the soil amoeba Acanthamoeba
castellanii. D. Lloyd, B. Kristensen & H. Degn. J. Gen. Microbiol.
126, 167-I70 (1981). |
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| 2 |
The effects of cyanide, azide, carbon
monoxide and salicylhydroxamic acid on whole cell respiration of Acanthamoeba
castellanii. D. Lloyd, B. Kristensen & H. Degn. J. Gen. Microbiol.
128, 185-188 (1981). |
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| 3 |
Glycolysis and respiration in yeasts:
The Pasteur effect studied by mass spectrometry. D. Lloyd, B. Kristensen
& H. Degn. Biochem. J. 212, 749-754 (1983). |
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| 4 |
Glycolysis and respiration in yeasts:
the effect of NH4+ in yeasts studied by mass
spectrometry. D. Lloyd, B. Kristensen & H. Degn. J. Gen. Microbiol.
129, 2125-2127 (1983). |
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| 5 |
The presence of O2 in rumen
liquor and its effects on methanogenesis. R. I. Scott, N. Yarlett,
K. Hillman, T. N. Williams, A. G. Williams & D. Lloyd. J. App.
Bacteriol. 55, 143-149 (1983). |
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| 6 |
A note on the effects of hydrogen production
by the rumen protozoon Dasytricha ruminantium Schuberg. N.
Yarlett, R. I. Scott, A. G Williarns & D. Lloyd. J. Appl. Bacteriol.
55, 359-361 (1983). |
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| 7 |
Direct measurement of methanogenesis
in anaerobic digesters by membrane inlet mass spectrometry. Scott,
R. I., Williams, T. N., Whitmore, T. N. & Lloyd, D. Europ. J. Applied
Microbiol. & Biotechnol. 18, 236-241 (1983). |
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| 8 |
Membrane inlet mass spectrometry - Measurement
of dissolved gases in fermentation liquids. Lloyd, D., Scott, R. I.
& Williams, T. N. Trends in Biotechnol. 1, 60-63 (1983). |
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| 9 |
Direct measurement of dissolved gases
in microbiological systems using membrane inlet mass spectrometry.
Lloyd, D. & Scott, R. I. J. Microbiol. Methods 1, 313-320
(1983). |
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| 10 |
Oxygen sensitivity of methanogenesis
in rumen and anaerobic digester populations using mass spectrometry.
Scott, R. I., Williams, T. N. & Lloyd, D. Biotechnol. Lett.
5, 375-380 (1983). |
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| 11 |
Metronidazole inhibition of hydrogen
production in vivo in drug-sensitive and resistant strains of Trichomonas
vaginalis. Lloyd, D. & Kristensen, B. J. Gen. Microbiol.
131, 849-853 (1985). |
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| 12 |
Comparative studies of methanogenesis
in thermophilic and mesophilic digesters using membrane inlet mass
spectrometry. T. N. Whitmore, M. Lazzari & D. Lloyd. Biotechnol.
Lett. 7, 283-288 (1985). |
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| 13 |
Measurement of dissolved gas concentrations
in ovine rumen liquor in situ using a portable quadrupole mass spectrometer.
K. Hillman, D. Lloyd & A. G Williams. Current Microbiol. 12,
335-340 (1985). |
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| 14 |
Inhibition of H2 production
in drug-resistant and susceptible strains by a range of nitroimidazole
derivatives. D. Lloyd, N. Yarlett & N. C. Yarlett. Biochem Pharmacol
35, 61-64 (1986). |
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| 15 |
Aerobic bacterial denitrification: the
rule rather than the exception. D. Lloyd, L. Boddy & K. J. P. Davies.
FEMS Microbiol. Ecology 45, 185-190 (1987). |
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| 16 |
Ferredoxin-dependent reduction of nitroimidazole
derivatives in drug-resistant and susceptible strains of Trichomonas
vaginalis. N. Yarlett, N. C. Yarlett and D. Lloyd. Biochem.
Pharmacol. 35, 1703-1708 (1986). |
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| 17 |
Hydrogen-dependent control of the continuous
anaerobic digestion process. T. N. Whitmore, G. Jones & D. Lloyd.
Appl. Microbiol. Biotechnol. 26, 383-388 (1987). |
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| 18 |
Mass spectrometry as an ecological tool
for in situ measurements of dissolved gases in sediment systems. D.
Lloyd, K. J. P. Davies & L. Boddy. FEMS Microbiol. Ecol.
38, 11-17 (1986). |
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| 19 |
Reduction of nitridazole by metronidazole
resistant and susceptible strains of Trichomonas vaginalis. N. Yarlett,
C. C. Rowlands, N. C. Yarlett, J. C. Evans & D. Lloyd. Parasitology
94, 93-99 (1987). |
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| 20 |
Methanogenesis from methanol in Methanosarcina
barkeri studied using membrane inlet mass spectrometry. G Ranalli,
T. N. Whitmore & D. Lloyd. FEMS Microbiol. Lett. 35,
119-123 (1986). |
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| 21 |
Metronidazole resistant clinical isolates
of Trichomonas vaginalis maintain low intracellular metronidazole
radical anion levels as a consequence of defective O2 scavenging.
D. Lloyd, N. Yarlett, N. C. Yarlett, J. Z. Pedersen & B. Kristensen.
Acta Universitatis CarolinaeBiologica 30, 521-528 (1988). |
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| 22 |
Mass spectrometric control of the thermophilic
anaerobic digestion process based on levels of dissolved hydrogen.
T. N. Whitmore & D. Lloyd. Biotechnology Letters 8,
203-208 (1986). |
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| 23 |
Respiration of the hydrogenosome-containing
fungus Neocalimastix patriciarum. N. Yarlett, C. Rowlands,
N. C. Yarlett, J. C. Evans & D. Lloyd. Arch. Microbiol. 148,
25-28 (1987). |
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| 24 |
The effects of O2 on fermentation
in Tritrichomonas foetus KV1 and its variant 1MR100 with defective
hydrogenosomes. D. Lloyd, C. J. James, A. L. Lloyd, N. Yarlett & N.
C. Yarlett. J. Gen. Microbiol. 133, 1181-1187 (1987). |
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| 25 |
The Pasteur Effect in Yeast: mass spectrometric
monitoring of O2 uptake and CO2 and ethanol
production. D. Lloyd & C. J. James. FEMS Microbiol. Lett. 42,
27-31 (1987). |
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| 26 |
Interactions between the methanogen Methanosarcina
barkeri and ciliate protozoa. K. Hillman, D. Lloyd & A. G. Williams.
Lett. Appl. Microbiol. 7, 49-53 (1988). |
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| 27 |
Hydrogen-dependent control of the continuous
thermophilic anaerobic digestion process using membrane inlet mass
spectrometry. D. Lloyd, T. N. Whitmore. Lett. Appl. Microbiol.
6, 5-10 (1987). |
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| 28 |
The influence of oxygen and organic hydrogen
acceptors on glycolytic CO2 production in Brettanomyces
anomalous. D. M. Gaunt, H. Degn, D. Lloyd. Yeast 4,
249-255 (1988). |
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| 29 |
Aerobic denitrification in Paracoccus
denitrificans and Pseudomonas aeruginosa. K. J. P. Davies,
D. Lloyd & L. Boddy. J. Gen. Microbiol. 135, 2445-2451. |
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| 30 |
Formate and glucose stimulation of methane
and hydrogen production in rumen liquor. J. E. Ellis, A. G Williams
& D. Lloyd. Current Microbiol. 20, 251-254 (1990). |
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| 31 |
Giardia lamblia produces alanine
anaerobically but not in the presence of oxygen. T. A. Paget, M. H.
Raynor, D. W. E. Shipp & D. Lloyd. Molecular. Biochem. Parasitology
42, 63-68 (1990). |
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| 32 |
Trichomonas vaginalis requires
traces of oxygen and high concentrations of carbon dioxide for optimal
growth. T. A. Paget & D. Lloyd (1990). Molec. Biochem. Parasitol.
41, 65-72. |
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| 33 |
Influence of CO2 and low concentrations
of O2 on fermentative metabolism of the ruminal ciliate
Polyplastron multivesciculatum. J. E. Ellis, P. S. McIntyre,
M. Saleh, A. G. Williams & D. Lloyd. Appl. Environ. Microbiol.
57, 1400-1407 (1991). |
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| 34 |
Influence of CO2 and low concentrations
of O2 on fermentative metabolism of the rumen ciliate Dasytricha
ruminantium. J. E. Ellis, P. S. McIntyre, M. Saleh, A. G. Williams
& D. Lloyd. J. Gen. Microbiol. 137, 1409-1417 (1991). |
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| 35 |
The parasitic flagellates Trichomonas
vaginalis and Tritrichomonas foetus produce indole and dimethyldisulphide:
direct characterization by membrane inlet tandem mass spectrometry.
D. Lloyd, F. R. Lauritsen & H. Degn. J. Gen. Microbiol. 137,
1743-47 (1991). |
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| 36 |
Identification of dissolved volatile
metabolites in microbial cultures by membrane inlet tandem mass spectrometry.
F. R. Lauritsen, D. Lloyd, S. Bohatka, L. T. Nielsen & H. Degn. Biological
Mass Spectrometry 60, 253-258 (1991). |
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| 37 |
Enzyme activity in organic solvent as
a function of water activity determined by membrane inlet mass spectrometry.
H. Degn, S. Bohatka & D. Lloyd. Biotechnology Techniques 6,
161-164 (1992). |
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| 38 |
The influence of ruminal concentrations
of O2 on fermentative metabolism of the rumen entodiniomorphid
ciliate, Eudiplodinium maggii. J. E. Ellis, P. S. McIntyre,
M. Saleh, A. G Williams & D. Lloyd. Current Microbiology 23,
245-251 (1991). |
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| 39 |
The effects of O2 on fermentation
in the intestinal parasite Giardia lamblia. T. A. Paget, M.
L. Kelly, E. L. Jarroll, D. G Lindmark & D. Lloyd. Mol. Biochem.
Parasitol. 57, 65-72 (1992). |
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| 40 |
Effects of alcohols on the respiration
and fermentation of aerated suspension of Baker's Yeast. H. N. Carlsen,
H. Degn & D. Lloyd. J. Gen. Microbiol. 137, 28792883
(1991). |
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| 41 |
Mutations in phosphofructokinases alter
the control characteristics of glycolysis in vivo in Saccharomyces
cerevisiae. D. Lloyd, C. J. James & P. K. Maitra. Yeast,
8, 291-301 (1992). |
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| 42 |
Influence of oxygen on the fermentative
metabolism of metronidazole-sensitive and resistant strains of Trichomonas
vaginalis. J. E. Ellis, D. Cole and D. Lloyd. Biochem. Molec.
Parasitol. 56, 79-88 (1992). |
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| 43 |
Rapid method for monitoring methanogenic
activities in mixed cell culture; effects of inhibitory compounds.
J. Benstead, D. B. Archer and D. Lloyd. Biotechnol. Techniques
7, 31-36. |
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| 44 |
Combined 13C-NMR and mass
spectrometry for non-invasive monitoring of metabolism. D. Lloyd,
C. J. James, A. Chapman & J. R. Dickinson. Biotechnol. Techniques,
6, 81-86 (1993). |
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| 45 |
Effects of growth with ethanol on fermentation
and membrane fluidity of Saccharomyces cerevisiae. D. Lloyd,
S. Morrell, H. N. Carlsen, H. Degn, P. E. James and C. C. Rowlands.
Yeast 9, 825-833 (1993). |
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| 46 |
Rapid and direct monitoring of volatile
fermentation products in the fungus Bjerkandera adusta by membrane
inlet mass spectrometry. F. R. Lauritsen, T. Kotiaho and D. Lloyd.
Biolog. Mass Spectrom. 22, 585-589 (1993). |
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| 47 |
Direct mass spectrometric measurement
of gases in peat cores. J. Benstead and D. Lloyd. FEMS Microbiol.
Ecol. 13, 233-240 (1994). |
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| 48 |
Effects of oxygen, pH and nitrate concentration
on denitrification by Pseudomonas species. K. L. Thomas, D. Lloyd
and L. Boddy. FEMS Microbiol. Lett. 118, 181-186 (1994). |
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| 49 |
Measurement of denitrification in estuarine
sediment using membrane inlet mass spectrometry. K. L. Thomas and
D. Lloyd. FEMS Microbiol. Ecol. 16, 103-114 (1995). |
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| 50 |
Spatial and temporal variations of dissolved
gases (CH4, CO2 and O2) in peat cores.
J. Benstead and D. Lloyd. Microbial Ecology 31 (1) 57-66
(1995). |
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| 51 |
A MIMS miniprobe for the direct simultaneous
measurement of multiple gas species. D. Lloyd, K. Thomas, D. Price,
B. O'Neil, K. Oliver and T. N. Williams. J. Microbiol. Meth.
(1996). 25, 145-151. |
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| 52 |
A comparison of different methods for
the measurement of dissolved gas gradients in waterlogged peat cores.
K. L. Thomas, D. Price and D. Lloyd. J. Microbiol. Meth. 24,
191-198 (1995). |
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| 53 |
Role of wetland plants in the diurnal
control of methane and carbon dioxide fluxes in peat. K. L. Thomas,
J. Benstead, K. L. Davies and D. Lloyd. Soil Biol. Biochem.
28, 17-23 (1996). |
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| 54 |
Gas diffusion coefficient profile in
peat deterrnined by modelling mass spectrometric data: implications
for gas phase distribution. K. D. Stephen, J. R. M. Arah, K. L. Thomas,
J Benstead and D. Lloyd. Soil Biol. Biochem (1998) 30,
429-431. |
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| 55 |
Oxygen Dependent Low Temperature n6 (~12)-Desaturase
Induction and Alteratio of Fatty Acid Composition in Acanthamoeba
castellanii. S. V. Avery, J. Rutter, J. L. Harwood and D. Lloyd.
Microbiology (1996) 142, 2213-2221. |
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| 56 |
Micro-ecology of peat: minimally
invasive analysis using confocal laser scannin microscopy, membrane
inlet mass spectrometry and PCR-amplification of methanogen-specific
gene sequences. D. Lloyd, K.L. Thomas, A. Hayes, B. Hill, B.A. Hales,
C. Edwards, J. R. Saunders, D.A. Ritchie and M. Upton. FEMS Microbial.
Ecol. 25, 179-188 (1998). |
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| 57 |
Diurnal oscillations of gas production
and effluxes (CO2 AND CH4) in cores from peat
bog. K.L. Thomas, D. Lloyd, J. Benstead and S.H. Lloyd. Biol. Rhythm
Res. 29 247-259 (1998). |
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| 58 |
Oxygen induces microsomal fatty acid
~12(n6) -desaturase independently of temperature in O2-limited cultures
of Acanthamoeba castellanii (1997) Thomas, K.L., Rutter, A.J., Suller,
M.T.E., Lloyd, D. & Harwood, J. FEBS Lett. 425, 171-174. |
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| 59 |
Methanogenesis and CO2 exchange
in an ombrotrophic peat bog. D.Lloyd, K.L.Thomas, J.Benstead, K.L.Davies,
S.H.Lloyd, J.R.M.Arah and K.D.Stephen, Atmospher. Environ.
(1998). 31, 3229-3238. |
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| 60 |
N2, N2O and 02
profiles in a Tagus estuary salt marsh sediment. Cartaxana, P and
Lloyd, D. Coastal and Shelf Science 48, 751-756. |
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| 61 |
Electrospray mass spectrometry for assay
of erythromycin A extracted from fermentation liquor. Morgan, J.,
Rowlands, R. T., Joyce-Menekse, M. E., Gilbert, I. H. & Lloyd, D.
Biotechnol. Techn (1998). 12, 435-439. |
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| 62 |
Photosynthesis and gas dynamics in an
estuarine sediment: sub-millimeter resolution profiles using membrane
inlet mass spectrometry. Cowie, G & Lloyd, D.(In preparation.) |
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| 63 |
Nitrite Inhibits Hydrogen Production
and Kills the Cattle Parasite Tritric foetus. Lloyd, D & James C J
(In preparation.) |
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| 64 |
Membrane inlet ion trap mass spectrometry
for the direct measurement of dissolved gas in ecological samples.
Cowie, G & Lloyd, D. J. Microbial Meth. 25, 1-12. |
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| 65 |
Yeast Vitality During Cider Fermentation:
Assessment By Energy Metabolism. Dinsdale, M. G, Lloyd, D., McIntyre,
P. & Jarvis, B. Yeast (1999). 15, 285-293. |
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| 66 |
Anoxic function for the E.coli flavohaemoglobin
(Hmp): reversible binding of NO and reduction to N2O. Kim,
S.O., Orii, Y., Lloyd, D., Hughes, M. N. and Poole, R. L. C. FEBS
Lett. 445, 389-394 (1999). |
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| 67 |
Kinetics, stereospecificity and expression
of the malolactic enzyme. C. Authurs and D. Lloyd, Appl. Environ.
Microbiol. 65, 3360-3363 (1999). |
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| 68 |
Rapid and Sensitive Quantitation of Antibiotics
in Fermentations by Electrospray Mass Spectrometry. Janine Morgan,
Miranda E. Joyce-Menekse, Robert T. Rowlands, Ian H. Gilbert and David
Lloyd (2000). |
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| 69 |
Extraction and identification of volatile
organic substances (VOS) from Scottish peat cores. Beckmann, M. &
Lloyd, D. Atmospheric Environment, (2000). |
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| 70 |
Mass spectrometric monitoring of gases
(CO2, CH4, 02) in peat cores from
Kopparas Mire, Sweden. Beckmann, M. & Lloyd, D. Gobal Change Biology,
(2000) |
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| 71 |
Aromatic interconversions in the white-rot
fungus Bjerkandera adusta. Lunding, A. Lauritsen, F. R. & Lloyd,
D. Enz. Microb. Technol (2000). |
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| 72 |
Tammam, J.D., Williams, A.G., Banks,
J., Cowie, G & Lloyd, D. (2000). Membrane inlet mass spectrometric
measurement of 02 and CO2 gradients in a developing
Cheddar cheese ecosystem. Int. J. Food Microbiol. [In Press]. |
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